ea0073pep13.7 | Presented ePosters 13: Pituitary and Neuroendocrinology | ECE2021
Filipowicz Dorota
, Krygier Aleksandra
, Ewelina Szczepanek-Parulska
, Domagalska Maja
, Ruchala Marek
IntroductionHepcidin, main body iron regulator protein, decreases iron concentration available for erythropoiesis. Oppositely, excessive erythropoiesis in acromegaly patients (increased GH and IGF-1), may inhibit hepcidin production. GH stimulates bone marrow, whereas IGF-1 receptors are expressed in erythrocytes. Exogenous GH administration in healthy subjects reduced hepcidin level. The role of hepcidin in iron metabolism of acromegaly patients has not...